What condition is associated with an increased risk in patients with diabetes mellitus?

What condition is associated with an increased risk in patients with diabetes mellitus?

• A. Ascariasis
• B. Cholangitis
• C. Gangrenous Cholecystitis
• D. Biliary sludge

Answer: (C)

Gangrenous cholecystitis is a condition that occurs when the gallbladder becomes inflamed and is characterized by necrosis due to a lack of blood supply. In patients with diabetes mellitus, there are several reasons why this condition is more prevalent. Diabetes is known to impair immune function, making individuals more susceptible to infections. Additionally, the presence of hyperglycemia can affect vascular health; it can lead to narrowing of blood vessels and compromised blood flow, which increases the likelihood of ischemia in the gallbladder. Moreover, patients with diabetes often have concomitant conditions, such as obesity and metabolic syndrome, which increase the risk of gallstone formation. Gallstones can obstruct the cystic duct, leading to inflammation and potential complications, such as gangrenous cholecystitis. The combination of these factors highlights why diabetic patients have a higher risk of developing this particular condition compared to the others listed. While other options may have varying associations with diabetes, they do not present the same level of increased risk or direct correlation as gangrenous cholecystitis, particularly in the context of the complications stemming from poor glycemic control and immune dysfunction in diabetic patients.

Gangrenous cholecystitis is a condition that occurs when the gallbladder becomes inflamed and is characterized by necrosis due to a lack of blood supply. In patients with diabetes mellitus, there are several reasons why this condition is more prevalent. Diabetes is known to impair immune function, making individuals more susceptible to infections. Additionally, the presence of hyperglycemia can affect vascular health; it can lead to narrowing of blood vessels and compromised blood flow, which increases the likelihood of ischemia in the gallbladder.

Moreover, patients with diabetes often have concomitant conditions, such as obesity and metabolic syndrome, which increase the risk of gallstone formation. Gallstones can obstruct the cystic duct, leading to inflammation and potential complications, such as gangrenous cholecystitis. The combination of these factors highlights why diabetic patients have a higher risk of developing this particular condition compared to the others listed.

While other options may have varying associations with diabetes, they do not present the same level of increased risk or direct correlation as gangrenous cholecystitis, particularly in the context of the complications stemming from poor glycemic control and immune dysfunction in diabetic patients.